Interstate 85 provides the major transportation route for the Upstate of South Carolina, linking together the major centers of Greenville and Spartanburg with regional centers of importance.
Georgia state line to Greenville
In South Carolina, Interstate 85 bypasses Clemson and Anderson on the way to Greenville. Beginning at Anderson, I-85 widens from four to six lanes. Near Powdersville, U.S. 29 joins I-85 and they run concurrently until they cross the Saluda River.
Greenville to Spartanburg
Interstate 85 bypasses just south of Greenville, but provides two links into the city via spur routes Interstates 185 and 385. U.S. 29 splits from I-85 and joins I-185 toward downtown Greenville. I-185 recently saw a major expansion south of the city as the Southern Connector was completed. In this section, the roadway is six to eight lanes wide, depending on the location.
Much of the Upstate's industrial, institutional, and commercial base is located along I-85, especially with regards to the growing automotive industry. The North American headquarters for Michelin, along with a major BMW assembly plant, and the new Clemson University International Center for Automobile Research are all visible from the road. Additional companies have major operations along this corridor, including Hubbell Lighting, Sara Lee, Hitachi, and General Electric. I-85 also bypasses Greenville-Spartanburg International Airport, which serves the Greenville-Spartanburg metropolitan area.
Spartanburg to North Carolina state line
Instead of going into Spartanburg, I-85 bypasses the city to the north. Its original route is now signed Business Loop 85 and was approved by AASHTO on April 22, 1995.
North of Spartanburg, I-85 narrows from six lanes back to four lanes and bypasses Gaffney. At Gaffney, motorists can see The Peachoid, a large water tower with its top shaped like a peach, which is one of the state's most important crops.
Much of the terrain between Spartanburg and the North Carolina border is rural in nature.